INCREASED LIPID PEROXIDES AND INFLAMMATORY PARAMETERS IN THE RETINA ADJACENT TO CHOROIDAL MELANOMA

Authors
AUGUSTIN AJ BOKER T BREIPOHL W
Citation
Aj. Augustin et al., INCREASED LIPID PEROXIDES AND INFLAMMATORY PARAMETERS IN THE RETINA ADJACENT TO CHOROIDAL MELANOMA, British journal of ophthalmology, 78(2), 1994, pp. 130-132
Citations number
8
Categorie Soggetti
Ophthalmology
Journal title
British journal of ophthalmology → ACNP
ISSN journal
00071161
Volume
78
Issue
2
Year of publication
1994
Pages
130 - 132
Database
ISI
SICI code
0007-1161(1994)78:2<130:ILPAIP>2.0.ZU;2-Z
Abstract
Oxidative tissue damage and inflammatory reaction were investigated in the neurosensory retina of five eyes with malignant choroidal melanom a and correlated to the distance from the tumour. The results showed e levated levels of both Lipid peroxides (expressed as thiobarbituric ac id reactive substances) and myeloperoxidase in the retina adjacent to the tumour. The values declined with distance from the tumour. The res ults indicate that production of oxygen free radicals contributes to t umour associated retinopathy.