TOXIC EFFECT ON HUMAN SPERMATOZOA BY CHLAMYDIA-TRACHOMATIS PURIFIED LIPOPOLYSACCHARIDE

Authors
GALDIERO F SOMMESE L GORGA F GALDIERO E RIZZO A AJELLO M
Citation
F. Galdiero et al., TOXIC EFFECT ON HUMAN SPERMATOZOA BY CHLAMYDIA-TRACHOMATIS PURIFIED LIPOPOLYSACCHARIDE, FEMS microbiology letters, 115(2-3), 1994, pp. 197-200
Citations number
16
Categorie Soggetti
Microbiology
Journal title
FEMS microbiology letters → ACNP
ISSN journal
03781097
Volume
115
Issue
2-3
Year of publication
1994
Pages
197 - 200
Database
ISI
SICI code
0378-1097(1994)115:2-3<197:TEOHSB>2.0.ZU;2-4
Abstract
We have investigated the effect that lipopolysaccharide extracted from Chlamydia trachomatis has on human spermatozoa. A lipopolysaccharide of 0.1 mu g ml(-1) caused a spermatozoa mortality rate of 65+/-4% eval uated by eosin exclusion test. The toxic activity occurred rapidly eve n after brief incubation times, reaching the maximum (100% mortality) within 60 min.