SINGLE-LUNG TRANSPLANTATION AS TREATMENT FOR END-STAGE PULMONARY SARCOIDOSIS - RECURRENCE OF SARCOIDOSIS IN 2 DIFFERENT LUNG ALLOGRAFTS IN ONE PATIENT

Three patients have undergone single lung transplantation in our hospi tal because of respiratory failure as a result of sarcoidosis. Two pat ients survived the postoperative period. Obliterative bronchiolitis de veloped in one of these patients, and recurrence of sarcoidosis in the transplanted lung necessitated contralateral single lung transplantat ion. Nine months later the first transplant became necrotic and infect ed and had to be removed. The postoperative course was uncomplicated. However, transbronchial biopsy specimens 10 months after retransplanta tion show sarcoid changes also in the second transplant, but without a ny signs of cellular rejection.