THERAPY WITH URSODEOXYCHOLIC ACID IN CHOLESTATIC LIVER-DISEASE

Authors
VANDEMEEBERG PC VANERPECUM KJ VANBERGEHENEGOUWEN GP
Citation
Pc. Vandemeeberg et al., THERAPY WITH URSODEOXYCHOLIC ACID IN CHOLESTATIC LIVER-DISEASE, Scandinavian journal of gastroenterology, 28, 1993, pp. 15-20
Citations number
71
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Scandinavian journal of gastroenterology → ACNP
ISSN journal
00365521
Volume
28
Year of publication
1993
Supplement
200
Pages
15 - 20
Database
ISI
SICI code
0036-5521(1993)28:<15:TWUAIC>2.0.ZU;2-4
Abstract
Ursodeoxycholic acid (UDCA) has beneficial effects on symptoms, liver biochemistry and, possibly, liver histology in primary biliary cirrhos is and other cholestatic liver diseases. UDCA may exert these benefici al effects by a direct hepatoprotective effect, by influencing the ent erohepatic circulation of endogenous bile salts, by enhancing bile flo w through a cholehepatic shunt mechanism or by immune modulation. In t he present article, established and potential indications for UDCA are reviewed.