B. Gottschalk et al., SUBTLE SPEECH AND MOTOR DEFICITS OF CHILDREN WITH CONGENITAL HYPOTHYROID TREATED EARLY, Developmental Medicine and Child Neurology, 36(3), 1994, pp. 216-220
This study surveyed the development and functioning of a group of 16 c
hildren with congenital hypothyroidism who had been followed closely s
ince treatment was instituted at an average age of 15.6 days. This gro
up of early-treated young children had no deficits in cognitive or ada
ptive functioning. Some isolated motor deficits were found, although r
esults of the Finger-tapping and Marching subtests of the Reitan-India
na battery did not replicate the New England Congenital Hypothyroid Co
llaborative (1985) finding of impaired performance. Speech deficits we
re documented in some. Congenitally hypothyroid children with delayed
neonatal bone-age performed more poorly on most measures than those wh
ose bone-age had been normal at birth.