Ultrasonography is an integral part of the radiological imaging of mal
ignant lymphomas for staging, therapy planning, monitoring, follow-up,
post-therapeutic care, and detection of recurrences, as well as the d
iagnostic differentiation of benign lesions and metastasis of solid tu
mors. None of the imaging methods, including sonography, however, can
safely determine the stage (UICC certainty level C4) in agreement with
the pathohistological examination. Also considering the clinical appe
arance the sonographic criteria in the synoptic evaluation will nevert
heless provide important indications for diagnosis and therapy plannin
g. Not only changes in size and shape, but also the echogenicity (gray
-scale histogram) and vascularization (color Doppler) of nodal and ext
ranodal processes are decisive criteria for estimating the therapeutic
response rates and detecting relapses.