SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW ARACHIDONIC-ACID ANALOGS

Authors
LEGALL T DEMONTARBY L GREE R MILLET J SEPULCHRE C BELLAMY F
Citation
T. Legall et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW ARACHIDONIC-ACID ANALOGS, Bioorganic & medicinal chemistry letters, 4(2), 1994, pp. 247-252
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
2
Year of publication
1994
Pages
247 - 252
Database
ISI
SICI code
0960-894X(1994)4:2<247:SABEON>2.0.ZU;2-Z
Abstract
New arachidonic acid analogs selectively modified at the C-10 position have been prepared. Several of them are potent and selective leukotri ene biosynthesis inhibitors and preliminary structure-activity relatio nships in these series are described.