SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW LTA(4) ANALOGS

Authors
LEGALL T GREE R MILLET J SEPULCHRE C BELLAMY F
Citation
T. Legall et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW LTA(4) ANALOGS, Bioorganic & medicinal chemistry letters, 4(2), 1994, pp. 257-260
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
2
Year of publication
1994
Pages
257 - 260
Database
ISI
SICI code
0960-894X(1994)4:2<257:SABEON>2.0.ZU;2-W
Abstract
New stable leukotriene A(4) analogs with the epoxide ring replaced by isoxazole or isoxazoline have been synthesized. These derivatives have proven to be weak leukotriene biosynthesis inhibitors or receptor ant agonists.