SYNTHESES OF HOMOSERINE PHOSPHATE ANALOGS AS POTENTIAL INHIBITORS OF BACTERIAL THREONINE SYNTHASE

Authors
HARDE C NEFF KH NORDHOFF E GERBLING KP LABER B POHLENZ HD
Citation
C. Harde et al., SYNTHESES OF HOMOSERINE PHOSPHATE ANALOGS AS POTENTIAL INHIBITORS OF BACTERIAL THREONINE SYNTHASE, Bioorganic & medicinal chemistry letters, 4(2), 1994, pp. 273-278
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
2
Year of publication
1994
Pages
273 - 278
Database
ISI
SICI code
0960-894X(1994)4:2<273:SOHPAA>2.0.ZU;2-2
Abstract
The syntheses of five homoserine phosphate analogs (1-4, Z-5) are desc ribed. A brief summary of their potential to inhibit threonine synthas e from Escherichia coli is given.