INHERITED PREDISPOSITION TO COLORECTAL NEOPLASIA

Authors
STEPHENSON BM HALL NR FINAN PJ BISHOP T
Citation
Bm. Stephenson et al., INHERITED PREDISPOSITION TO COLORECTAL NEOPLASIA, British Journal of Hospital Medicine, 51(1-2), 1994, pp. 15-23
Citations number
38
Categorie Soggetti
Medicine, General & Internal
Journal title
British Journal of Hospital Medicine → ACNP
ISSN journal
00071064
Volume
51
Issue
1-2
Year of publication
1994
Pages
15 - 23
Database
ISI
SICI code
0007-1064(1994)51:1-2<15:IPTCN>2.0.ZU;2-M
Abstract
This review concentrates on the genetics of colorectal neoplasia. Ther e is now a greater understanding of the molecular genetics of the inhe rited condition familial adenomatous polyposis and of the adenoma-carc inoma sequence in non-inherited colorectal cancer. We consider the evi dence that sporadic colorectal cancer may also have an underlying gene tic susceptibility.