INFLUENCE OF PH AND TEMPERATURE ON THE STRUCTURE IN MACROMOLECULAR SOLUTIONS - A PRELIMINARY SANS STUDY ON LYSOZYME

In this paper we present some preliminary Small Angle Neutron Scatteri ng results about the influence of pH and temperature on the structure of macromolecular solutions. We have investigated aqueous solutions of lysozyme at concentrations of 0.05, 0.10 and 0.15 w/w, at pH values o f about 3, 5, and 6.7, and in the temperature range of 10-50-degrees-C . At the lower values of the pH, well defined interaction peaks are pr esent in the scattered intensities, whereas at the higher pH an unstru ctured aggregation takes place, which is reduced by the increase in te mperature.