EUONYMOSIDE-A - A NEW CYTOTOXIC CARDENOLIDE GLYCOSIDE FROM THE BARK OF EUONYMUS-SIEBOLDIANUS

Authors
BAEK NI LEE YH PARK JD KIM SI AHN BZ
Citation
Ni. Baek et al., EUONYMOSIDE-A - A NEW CYTOTOXIC CARDENOLIDE GLYCOSIDE FROM THE BARK OF EUONYMUS-SIEBOLDIANUS, Planta medica, 60(1), 1994, pp. 26-29
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
60
Issue
1
Year of publication
1994
Pages
26 - 29
Database
ISI
SICI code
0032-0943(1994)60:1<26:E-ANCC>2.0.ZU;2-W
Abstract
A new cytotoxic cardenolide glycoside, euonymoside A (1), was isolated from the bark of Euonymus sieboldianus. The structure of 1 was elucid ated as acovenosigenin A-3-0-beta-D-glucopyranosyl (1-->2)-alpha-L-rha mnopyranoside. The IC50 values of 1 against A549 (human lung carcinoma ) and SK-OV-3 (human ovary adenocarcinoma) were 0.06 and 0.4 mu g/ml, respectively.