CYTOTOXIC AND ANTIBACTERIAL LABDANE-TYPE DITERPENES FROM THE AERIAL PARTS OF CISTUS-INCANUS SUBSP CRETICUS

Authors
CHINOU I DEMETZOS C HARVALA C ROUSSAKIS C VERBIST JF
Citation
I. Chinou et al., CYTOTOXIC AND ANTIBACTERIAL LABDANE-TYPE DITERPENES FROM THE AERIAL PARTS OF CISTUS-INCANUS SUBSP CRETICUS, Planta medica, 60(1), 1994, pp. 34-36
Citations number
19
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
60
Issue
1
Year of publication
1994
Pages
34 - 36
Database
ISI
SICI code
0032-0943(1994)60:1<34:CAALDF>2.0.ZU;2-X
Abstract
Seven labdane-type diterpenoids were isolated from the leaves of Cistu s incanus subsp. creticus; their structures were established by spectr oscopic means. AU compounds were tested in vitro for their cytotoxicit y against three cell line systems: KB, P-388; and NSCLC-NG. Their anti bacterial and antifungal activities were tested against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosae, Enteroba cter cloacae, Escherichia coli, Klebsiella pneumonia, Torulopsis glabr ata, Saccharomyces cerevisiae, and Candida albicans as well.