IN-VITRO INHIBITION OF CYCLOOXYGENASE AND 5-LIPOXYGENASE BY ALKAMIDESFROM ECHINACEA AND ACHILLEA SPECIES

Authors
MULLERJAKIC B BREU W PROBSTLE A REDL K GREGER H BAUER R
Citation
B. Mullerjakic et al., IN-VITRO INHIBITION OF CYCLOOXYGENASE AND 5-LIPOXYGENASE BY ALKAMIDESFROM ECHINACEA AND ACHILLEA SPECIES, Planta medica, 60(1), 1994, pp. 37-40
Citations number
19
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
60
Issue
1
Year of publication
1994
Pages
37 - 40
Database
ISI
SICI code
0032-0943(1994)60:1<37:IIOCA5>2.0.ZU;2-9
Abstract
Polyunsaturated alkamides isolated from Achillea species, Echinacea an gustifolia DC., Anacyclus pyrethrum (L.) Link, and Aaronsohnia pubesce ns (Desf.) Bremer & Humphries, (Compositae) were shown to possess inhi bitory activity in in vitro cyclooxygenase (sheep seminal microsomes) and 5-lipoxygenase (porcine leukocytes) assays. Activity appeared to d epend on the particular structure of the alkamides.