Ga. Bernstein et al., CAFFEINE EFFECTS ON LEARNING, PERFORMANCE, AND ANXIETY IN NORMAL SCHOOL-AGE-CHILDREN, Journal of the American Academy of Child and Adolescent Psychiatry, 33(3), 1994, pp. 407-415
Objective: The purpose of this investigation was to study the acute ef
fects of caffeine on learning, performance, and anxiety in normal prep
ubertal children. Method: Twenty-one children were evaluated in a doub
le-blind, placebo-controlled crossover design. Subjects were studied d
uring four sessions, 1 week apart, under the following conditions: bas
eline, placebo, 2.5 mg/kg caffeine, and 5.0 mg/kg caffeine. Subjects w
ere randomized to order of placebo and the two dosages of caffeine. De
pendent measures included tests of attention, manual dexterity, short-
term memory, and processing speed. Anxiety rating scales were also adm
inistered. Saliva samples were analyzed for caffeine levels. Results:
Caffeine improved performance on two of four measures of the Test of V
ariables of Attention and on a test of manual dexterity in the dominan
t hand. There was a trend toward increased current level of self-repor
ted anxiety after caffeine on a visual analogue measure of anxiety. Ch
ildren reported feeling significantly less ''sluggish'' after caffeine
ingestion than after placebo ingestion. Conclusions: In a small sampl
e size, there was indication that caffeine enhanced performance on a t
est of attention and on a motor task. Children also reported feeling l
ess ''sluggish'' but somewhat more anxious. Because caffeine is so wid
ely available and frequently consumed by children, these results are i
mportant and need replication.