Sh. Kapiga et al., RISK-FACTORS FOR HIV-INFECTION AMONG WOMEN IN DAR-ES-SALAAM, TANZANIA, Journal of acquired immune deficiency syndromes, 7(3), 1994, pp. 301-309
To identify risk factors for HIV infection among women not known to be
members of high-risk groups in Dar-es-Salaam, Tanzania, and assess as
sociations between contraceptive use and HIV infection, we conducted a
cross-sectional case-control study at three representative family pla
nning clinics. Between February 1991 and June 1992, we enrolled 2,285
women; women were interviewed using a structured questionnaire, and sp
ecimens were collected for laboratory diagnosis of HIV and other sexua
lly transmitted diseases (STDs). The overall HIV prevalence was 11.5%
(95% CI: 10.2-12.8). Other prevalent STDs included gonorrhea (4.2%), t
richomoniasis (14.3%), candidiasis (11.5%), and syphilis (2.5%). HIV s
eroprevalence was significantly lower among younger women and women in
nonpolygamous marriages. HIV risk increased with both women's educati
on and male partner's education. Number of sex partners in the last 5
years was positively associated with HIV risk; however, among HIV-sero
positive women, the median number of sexual partners was only two. For
married women with only a single partner, their risk increased signif
icantly if their husbands had other partners. The risk of HIV infectio
n was higher among subjects with STDs, although only significantly so
for gonorrhea (OR 1.95, 95% CI: 1.10-3.45). After controlling for know
n and potential risk factors, the risk of HIV infection was significan
tly increased among women who had ever used an intrauterine device (IU
D) (OR 2.50, 95% CI: 1.35-4.64). Use of other contraceptives, includin
g oral contraceptives, was not significantly associated with HIV infec
tion. Our findings confirm that HIV and STDs are a major public health
problem among women in Dar-es-Salaam. Prospective data are needed to
confirm the association between HIV and the use of an IUD. Interventio
ns involving both women and men are urgently needed to reduce further
spread of HIV/STDs in this population.