PROGNOSTIC VALUE FROM DNA QUANTIFICATION BY STATIC CYTOMETRY IN BREAST-CANCER

OBJECTIVE: To determine if DNA quantification on fine needle aspiratio n (FNA) has predictive value in breast cancer. STUDY DESIGN: Forty-nin e patients with breast cancer were selected for this study because of their common characteristics. The smears were studied using image cyto metry. RESULTS: With the type of histogram and value of entropy, two l arge groups, with high and low degrees of malignancy, were obtained. S urvival teas utilized as a variable of interest. Kaplan-Meier survival curves for both groups were formulated, and the results were supporte d with statistical data. CONCLUSION: The survival differences between both groups were statistically significant (P<.001), thus demonstratin g the predictive value gf DNA quantification.