ACCEPTOR ANALOGS AS POTENTIAL INHIBITORS OF BOVINE BETA-1,4-GALACTOSYL TRANSFERASE

Authors
FIELD RA NEVILLE DCA SMITH RW FERGUSON MAJ
Citation
Ra. Field et al., ACCEPTOR ANALOGS AS POTENTIAL INHIBITORS OF BOVINE BETA-1,4-GALACTOSYL TRANSFERASE, Bioorganic & medicinal chemistry letters, 4(3), 1994, pp. 391-394
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
3
Year of publication
1994
Pages
391 - 394
Database
ISI
SICI code
0960-894X(1994)4:3<391:AAAPIO>2.0.ZU;2-D
Abstract
A series of 4- and B-substituted derivatives of benzyl N-acetyl-beta-( D) under bar-glucosaminide were prepared and assessed as inhibitors of bovine beta-1,4-galactosyl transferase. Of the azido, amino, and acet amido compounds tested, only the 4-amino compound (2) produced signifi cant inhibition of this enzyme.