In recent years, the aetiology of alcohol misuse has come to be concep
tualised in terms of risk factor models. Risk can emanate from a numbe
r of sources ranging from the genetic to the sociostructural. This cha
pter reviews the major environmental risk factors under two broad head
ings - those that affect the availability of the agent and those that
affect the vulnerability of the host. The former include a variety of
economic, social and physical factors such as price, advertising and l
icensing laws. The latter include broad socioeconomic and sociocultura
l factors, as well as interpersonal influences such as family, peers,
employment and stress. Practitioners (as distinct from policy-makers)
concerned with prevention and treatment of alcohol misuse can most eff
ectively intervene at the interpersonal level, and the paper concludes
with a discussion of the implications for clinical practice of the re
search reviewed in this domain.