CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION STUDIES OF PSORIASIN

Crystals of psoriasin, a protein related to the skin disease psoriasis , have been grown in two different crystal forms. Form I represents th e protein in the Ca2+-bound form, and form II represents the protein i n the Zn2+- and Ca2+-bound form. The crystals of form I are orthorhomb ic belonging to the space group P2(1)2(1)2(1) with cell parameters a=5 2.15, b=56.67 and c=76.38 Angstrom and diffract to 2.4 Angstrom. The c rystals of form II are tetragonal and belong to the space group P4(1(3 ))2(1)2 with cell parameters a=b=51.86, c=115.93 Angstrom and diffract to 2.0 Angstrom.