ELECTROCHEMICAL-BEHAVIOR OF PHARMACOLOGICALLY INTERESTING SELENOORGANIC COMPOUNDS .3. ORTHO-METHYLSELENO-BENZANILIDES

Authors
DAKOVA B LAMBERTS L EVERS M
Citation
B. Dakova et al., ELECTROCHEMICAL-BEHAVIOR OF PHARMACOLOGICALLY INTERESTING SELENOORGANIC COMPOUNDS .3. ORTHO-METHYLSELENO-BENZANILIDES, Electrochimica acta, 39(4), 1994, pp. 501-505
Citations number
27
Categorie Soggetti
Electrochemistry
Journal title
Electrochimica acta → ACNP
ISSN journal
00134686
Volume
39
Issue
4
Year of publication
1994
Pages
501 - 505
Database
ISI
SICI code
0013-4686(1994)39:4<501:EOPIS>2.0.ZU;2-V
Abstract
The electrochemical behaviour of 2-(methylseleno)benzanilide, one of t he major metabolites of Ebselen, together with a series of 2-methylsel eno-(4'-X-phenyl)benzamides were investigated by voltammetry using a r otating platinum electrode, cyclic voltammetry, controlled potential c oulometry and electrolysis. The measurements were realized in acetonit rile solution. The influence of temperature and acid on the nature of the oxidized products is shown. Comparison with their thio analogs is discussed.