A SHAPE FACTOR TO CHARACTERIZE THE QUALITY OF SPHEROIDS

Citation
F. Podczeck et Jm. Newton, A SHAPE FACTOR TO CHARACTERIZE THE QUALITY OF SPHEROIDS, Journal of Pharmacy and Pharmacology, 46(2), 1994, pp. 82-85
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
00223573
Volume
46
Issue
2
Year of publication
1994
Pages
82 - 85
Database
ISI
SICI code
0022-3573(1994)46:2<82:ASFTCT>2.0.ZU;2-#
Abstract
A shape factor e(R) has been devised to describe how the form of spher ical particles approaches that of a true spheroid, based on a two-dime nsional image analysis. Both the deviation of shape from a circle towa rds an ellipse and surface irregularities influence the value of e(R). Using a set of model figures such as squares, triangles, diamonds and stars, it could be shown that e(R) clearly differentiates between dif ferent polygonally symmetric figures, even in the case where common sh ape descriptors such as the aspect ratio provide equal values. The val ue of e(R) is 1.0 in the case of a perfect spheroid, while ellipticity and surface roughness lead to a significant change in the value.