P. Littlejohns et al., COMPARISON OF ASTHMATIC-PATIENTS ADMITTED TO HOSPITAL FROM HEALTH DISTRICTS EXPERIENCING HIGH AND LOW ASTHMA MORTALITY-RATES, Postgraduate medical journal, 70(820), 1994, pp. 92-99
Geographical variation in asthma mortality rates within the United Kin
gdom could be a reflection of variability in effectiveness of medical
care sen-ices, or epidemiological variation. In order to ascertain whe
ther differing hospital admission processes could contribute to this v
ariation, asthmatic patients admitted from two districts, experiencing
above and below average mortality rates were compared. The present st
udy was part of a cohort study of 1,200 consecutive acute adult admiss
ions in 1987/88. In the main study, social data and information on ref
erral were collected by interview for all patients. The admitting doct
ors' perception of the patient's severity was assessed on the basis of
the severity of symptoms, and likelihood of morbidity or mortality if
the patient was not admitted. Further information on asthmatic patien
ts (treatment and physiological measurements) was retrieved from the n
otes. Sixty-sis asthmatic patients resident in Wandsworth (a district
with high asthma mortality rates) were admitted to St George's Hospita
l or St James' Hospital (WW) and 31 patients resident in East Surrey (
ES) (a district with low asthma mortality rates) were admitted to the
East Surrey Hospital (ESH). Notes were obtained on 55 (83%) and 27 (87
%) of patients in the two districts, respectively, WW received signifi
cantly more patients by self-referral: 68% of patients called an ambul
ance or came directly to casualty compared with 30% in ES (chi-squared
= 13.7, d.f. = 2, P = < 0.001). There was a tendency for more admissi
ons to ESH to be taking oral steroids (chi-squared = 3.2, d.f. = 1, P
= 0.07). Patients admitted in WW tended to have more severe disease: 3
9 (85%) of patients admitted to WW had peak expiratory how less than 2
00 l/minute on admission compared to 14 (58%) in ES (chi-squared = 6,
d.f. = 1, P = 0.01). In WW the mean first recorded peak expiratory flo
w on admission was 154 l/minute compared to 172 l/minute in ES; their
mean peak how on discharge was 318 l/minute compared with 377 l/minute
in ES. Twenty-one (38%) of admissions in W:W were considered to be ve
ry urgent by the admitting hospital doctor compared to four (15%) in E
SH (chi-squared = 4.67, d.f. = 1, P = 0.03). This opportunistic study
found that, in an area experiencing high mortality rates, more patient
s with severe disease were admitted to hospital compared to a low mort
ality area. This does not appear to be due to differing hospital pract
ices but rather to increased levels of morbidity in the community. As
patients with more severe asthma are at a greater risk of dying, these
findings reinforce the need to standardize asthma treatment in the co
mmunity.