E. Arakawa et al., SOME FEATURES OF RNA FOLDING STRUCTURES OF CYTOCHROME-C-OXIDASE SUBUNIT-II AND CYTOCHROME-P450, Computer applications in the biosciences, 10(1), 1994, pp. 7-9
We have defined the folding index of the RNA secondary structure and c
ompared the value of this index obtained from a given RNA molecule wit
h one from the random sequences with the same A, U, G, C ratio. The mR
NA of the cytochrome c oxidase subunit II and cytochrome P450 from var
ious species was analyzed. We found that the mRNA of these genes were
more folded than the random sequences and the coding regions of these
mRNA were as equally folded as the random sequences. This result sugge
sts that the coding region of these mRNA has no more important seconda
ry structure than have the random sequences with the same A, U, G, C r
atio.