ELABORATION AND USE OF NICKEL PLANAR MACROCYCLIC COMPLEX-BASED SENSORS FOR THE DIRECT ELECTROCHEMICAL MEASUREMENT OF NITRIC-OXIDE IN BIOLOGICAL MEDIA

Authors
BEDIOUI F TREVIN S DEVYNCK J LANTOINE F BRUNET A DEVYNCK MA
Citation
F. Bedioui et al., ELABORATION AND USE OF NICKEL PLANAR MACROCYCLIC COMPLEX-BASED SENSORS FOR THE DIRECT ELECTROCHEMICAL MEASUREMENT OF NITRIC-OXIDE IN BIOLOGICAL MEDIA, Biosensors & bioelectronics, 12(3), 1997, pp. 205-212
Citations number
39
Categorie Soggetti
Biothechnology & Applied Migrobiology",Biophysics
Journal title
Biosensors & bioelectronics → ACNP
ISSN journal
09565663
Volume
12
Issue
3
Year of publication
1997
Pages
205 - 212
Database
ISI
SICI code
0956-5663(1997)12:3<205:EAUONP>2.0.ZU;2-Q
Abstract
We describe here the electrochemical detection of nitric oxide, NO, in biological systems by using chemically modified ultramicro carbon ele ctrodes. In the first part of the paper, the different steps involved in the electrochemical preparation and characterization of the nickel- based sensor are described. This is illustrated by the use of nickel(I I) tetrasulfonated phthalocyanine complex. The second part of the pape r describes two examples of the direct electrochemical measurement of NO production in human blood platelets and endothelial cells from umbi lical cord vein. (C) 1997 Elsevier Science Limited.