SILICONE BREAST PROTHESES AND RHEUMATIC SYMPTOMS - A RETROSPECTIVE FOLLOW-UP-STUDY

Objectives-To determine whether women with silicone breast protheses h ave more rheumatic complaints than controls. Methods-The study include d 287 women who had silicone implanted between patient a female contro l of the same age was selected who had had an aesthetic operation in t he same year. A questionnaire was sent to this retrospective cohort of women with silicone breast protheses and controls. Results-Questionna ires were returned by 235 cases (82%) and 210 controls (73%). Patients reported more symptoms arising after surgery than controls (0.6 v 0.3 complaints per subject, p < 0.001). The average interval between surg ery and onset of complaints was 5.1 years for patients and 5.9 for con trols. Complaints presented by patients were: painful joints silicone (p < 0.005), burning eyes (p < 0.01), and implants. skin abnormalities (p < 0.005). Differences in the use of antirheumatic drugs or medical consultations related to rheumatic symptoms did not reach statistical significance. Further information obtained from the patients and cont rols reporting rheumatic symptoms did not reveal the presence of a spe cific syndrome in connection with silicone materials. Conclusion-Women with silicone breast protheses report more rheumatic complaints after silicone implantation than controls, but there is no evidence of incr eased prevalence of common rheumatic diseases.