UNDIFFERENTIATED (EMBRYONAL) SARCOMA OF THE LIVER IN AN ADULT PATIENTWITH METASTASIS OF THE HEART AND BRAIN

A 26-year-old woman with a tumor of the left liver lobe was admitted t o the hospital. After incomplete resection of the tumor and histologic al diagnosis of an undifferentiated (embryonal) sarcoma of the liver a combination chemotherapy with ifosfamide and epidoxorubicine was star ted. 11 months later brain metastases were diagnosed. Routine ultrasou nd examination of the heart disclosed a pericardial tumor infiltrating the left atrium of the heart. After radiation therapy of the brain me tastases the patient was treated with two cycles of high-dose ifosfami de and epidoxorubicin. Two years after diagnosis the patient developed signs of cardiac failure and died. Postmortem autopsy confirmed the l ocal recurrence of the liver neoplasm and revealed its continuous spre ad to the pericardium via the diaphragm and infiltration of the left a trium.