COCAINE AND METABOLITES IN THE HAIR OF ANCIENT PERUVIAN COCA LEAF CHEWERS

Authors
SPRINGFIELD AC CARTMELL LI AUFDERHEIDE AC BUIKSTRA J HO J
Citation
Ac. Springfield et al., COCAINE AND METABOLITES IN THE HAIR OF ANCIENT PERUVIAN COCA LEAF CHEWERS, Forensic science international, 63(1-3), 1993, pp. 269-275
Citations number
17
Categorie Soggetti
Medicine, Legal
Journal title
Forensic science international → ACNP
ISSN journal
03790738
Volume
63
Issue
1-3
Year of publication
1993
Pages
269 - 275
Database
ISI
SICI code
0379-0738(1993)63:1-3<269:CAMITH>2.0.ZU;2-#
Abstract
Cocaine and its metabolites, benzoylecgonine (BZE) and ecgonine methyl ester (EME), were found in hair samples from ancient Peruvian coca-lea f chewers dating back to AD 1000. Hair was analyzed by gas chromatogra phy/mass spectrometry (GC/MS) to quantitate the concentrations. The tw o metabolites were found in higher concentration than the parent drug. The metabolite levels appear to be below that of modern cocaine abuse rs. Gender does not appear to be a factor in the incorporation of drug into hair.