W. Jochle, 40 YEARS OF CONTROL OF THE ESTROUS-CYCLE IN RUMINANTS - PROGRESS MADE, UNRESOLVED PROBLEMS AND THE POTENTIAL IMPACT OF SPERM ENCAPSULATION TECHNOLOGY, Reproduction, fertility and development, 5(6), 1993, pp. 587-594
Pharmacological control of the oestrous cycle may, with or without spe
rm encapsulation, remain an indispensable part of any attempt to make
artificial insemination available to the ranch-cattle industry. Of the
current methods, those most likely to remain acceptable with regulato
ry agencies and to gain acceptance with industry are those involving t
he short-term use (7-10 days) of minimal effective doses of progestins
(preferably progesterone) and the subsequent use of an analogue of pr
ostaglandin F-2 alpha. The use of microencapsulated sperm with a long
lifespan would allow artificial insemination to be achieved without re
ference to the time when heat and ovulation may occur.