A. Tham et al., IMPAIRED NEUROPSYCHOLOGICAL PERFORMANCE IN EUTHYMIC PATIENTS WITH RECURRING MOOD DISORDERS, The Journal of clinical psychiatry, 58(1), 1997, pp. 26-29
Background: Both patients suffering from schizophrenia and patients su
ffering from recurring mood disorder show cognitive impairments as est
ablished by a variety of neuropsychological tests. The aim of the pres
ent study was to investigate the neuropsychological performance of eut
hymic patients who had recurring mood disorder and the possible relati
onship between episodes of hospitalization and cognitive impairments.
Method: Twenty-six euthymic patients with a DSM-III-R recurring mood d
isorder diagnosis were investigated by using the Synonym Reasoning and
Block-Test Battery and a part of the Halstead-Reitan Test Battery. Re
sults: An overall lowered performance in the test results was found, T
here was a significant positive relationship between four different te
sts and the number of hospitalization episodes; the patients with impa
ired cognitive functioning had significantly more hospitalization epis
odes than patients with normal cognitive functioning. Conclusion: The
results suggest that a subgroup of patients with recurring mood disord
er are defined by more relapses and episodes of hospitalization and sh
ow cognitive dysfunctions even when euthymic.