MOLECULAR-CLONING AND SEQUENCING OF PORCINE SOMATOSTATIN RECEPTOR-2(+)

The porcine somatostatin receptor gene was isolated from a porcine gen omic library. Based on the deduced amino acid sequence, this gene enco des a 369 amino acid protein with seven hydrophobic segments, a charac teristic of G-protein coupled receptors, and shows only 13 amino acid difference (identity 96.5%, similarity 99.2%) in amino acid sequence f rom human somatostatin receptor 2. The data indicate that the amino ac id sequence is highly conserved in pig, human, rat and mouse somatosta tin receptor 2. (C) 1994 Academic Press, Inc.