FUNCTIONAL-RELATIONSHIP BETWEEN ESCHERICHIA-COLI RNASE-E AND THE CAFAPROTEIN

Authors
WACHI M UMITSUKI G NAGAI K
Citation
M. Wachi et al., FUNCTIONAL-RELATIONSHIP BETWEEN ESCHERICHIA-COLI RNASE-E AND THE CAFAPROTEIN, MGG. Molecular & general genetics, 253(4), 1997, pp. 515-519
Citations number
23
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
MGG. Molecular & general genetics → ACNP
ISSN journal
00268925
Volume
253
Issue
4
Year of publication
1997
Pages
515 - 519
Database
ISI
SICI code
0026-8925(1997)253:4<515:FBERAT>2.0.ZU;2-D
Abstract
We analyzed the functional relationship between the Escherichia coli R Nase E and the CafA protein, which show extensive sequence similarity. The temperature-sensitive growth of the RNase E mutant strain ams1 wa s partially suppressed by multicopy plasmids bearing the cafA gene. In troduction of a cafA::cat mutation enhanced the temperature sensitivit y of the ams1 mutant. These results suggest that there is a functional homology between these two proteins.