DNA-BINDING COMPOUNDS .5. SYNTHESIS AND CHARACTERIZATION OF BORON-CONTAINING BIBENZIMIDAZOLES RELATED TO THE DNA MINOR-GROOVE BINDER, HOECHST-33258

Authors
KELLY DP BATEMAN SA MARTIN RF REUM ME ROSE M WHITTAKER ARD
Citation
Dp. Kelly et al., DNA-BINDING COMPOUNDS .5. SYNTHESIS AND CHARACTERIZATION OF BORON-CONTAINING BIBENZIMIDAZOLES RELATED TO THE DNA MINOR-GROOVE BINDER, HOECHST-33258, Australian Journal of Chemistry, 47(2), 1994, pp. 247-262
Citations number
33
Categorie Soggetti
Chemistry
Journal title
Australian Journal of Chemistry → ACNP
ISSN journal
00049425
Volume
47
Issue
2
Year of publication
1994
Pages
247 - 262
Database
ISI
SICI code
0004-9425(1994)47:2<247:DC.SAC>2.0.ZU;2-1
Abstract
The synthesis and characterization of four novel boron-containing bibe nzimidazoles related to the DNA minor groove binder Hoechst 33258 are reported. Such compounds, particularly their B-10-enriched forms, have potential as agents for boron neutron capture therapy which is used i n the treatment of cancers.