Pain occurs in more than 80% of cancer patients before death. Because
of the increase in the frequency of cancer deaths worldwide, it is imp
erative to address cancer pain as a public health problem. Until recen
tly, educational efforts were focused on treatment issues rather than
adequate assessment. The approach to pain intensity as a multidimensio
nal construct has helped in focusing treatments and identifying progno
stic factors. Valid tools have been developed that allow multidiscipli
nary assessment of these prognostic factors and their complex interrel
ationship with the analgesic response. As a result of increased opioid
exposure, patients are currently developing newer toxicities, mostly
central excitability including delirium, myoclonus, grand mal seizures
, and hyperalgesia. The observation that more than 80% of patients wil
l require alternate routes for opioid delivery before death led to the
development of a number of novel and effective alternate routes for d
elivery. Finally, in recent years it has become evident that some spec
ific pain syndromes need to be addressed using specific assessment and
management techniques. Incidental pain, somatization, neuropathic pai
n, and cancer pain in patients with alcoholism and drug addiction are
some of these syndromes. (C) Acta Anaesthesiologica Scandinavica 41 (1
997).