We studied the ocular findings of two adult patients with the Eisenmen
ger's syndrome who had atrial septal defects that were diagnosed befor
e the age of 10 years but not operated on and pulmonary hypertension.
Both eyes of these patients showed microaneurysms, multiple small blot
hemorrhages, or capillary dilation in the temporal peripheral fundus.
Multiple microaneurysms and retinal collaterals were confirmed by flu
orescein angiography. One of the patients developed bilateral rubeosis
iridis with slow progression. These retinal lesions and the rubeosis
iridis are probably related to chronic ocular ischemia caused by chron
ic systemic hypoxia.