A NOVEL CLASS OF ANTITUMOR METABOLITES FROM THE FUNGUS NATTRASSIA-MANGIFERAE

Authors
CHU M TRUUMEES I PATEL MG GULLO VP BLOOD C KING I PAI JK PUAR MS
Citation
M. Chu et al., A NOVEL CLASS OF ANTITUMOR METABOLITES FROM THE FUNGUS NATTRASSIA-MANGIFERAE, Tetrahedron letters, 35(9), 1994, pp. 1343-1346
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
9
Year of publication
1994
Pages
1343 - 1346
Database
ISI
SICI code
0040-4039(1994)35:9<1343:ANCOAM>2.0.ZU;2-2
Abstract
Sch 49210, Sch 53514 and Sch 53516 has been isolated from a fungal cul ture, and identified by analysis of 2D NMR data. Two diacetylation der ivatives Sch 53515 and Sch 53517 has been synthesized. These compounds demonstrate inhibitory activity of phospholipase D (PLD), and display potent activity in the antitumor invasion chamber assay.