A TOTAL SYNTHESIS OF THE SESQUITERPENE QUINONE METACHROMIN-A

Authors
ALMEIDA WP CORREIA CRD
Citation
Wp. Almeida et Crd. Correia, A TOTAL SYNTHESIS OF THE SESQUITERPENE QUINONE METACHROMIN-A, Tetrahedron letters, 35(9), 1994, pp. 1367-1370
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
9
Year of publication
1994
Pages
1367 - 1370
Database
ISI
SICI code
0040-4039(1994)35:9<1367:ATSOTS>2.0.ZU;2-W
Abstract
The first total synthesis of the marine natural product metachromin A was accomplished through a convergent synthesis amenable to the prepar ation of synthetic analogues. The main features of this synthesis are the introduction of the oxygenation at C-17 employing a Thiele acetoxy lation reaction and a stereoselective Horner-Wadsworth-Emmons coupling