The sequential generation of dislocations in a strained epitaxial laye
r is considered. It is found that an additional work component results
from dislocation-dislocation interactions after some dislocations are
generated and located in the interface between the epitaxial layer an
d the substrate. The interaction energies induced by a single dislocat
ion and a dislocation array are derived. It is found that, in general,
when the distance between a fresh dislocation and the nearest pre-exi
sting dislocation is comparable to the layer thickness, the additional
work component achieves the level of the self energy of an isolated d
islocation. The additional work increases sharply with decreasing dist
ance between the fresh and pre-existing dislocations. If the spacing b
etween the dislocations exceeds approximately 20 times the layer thick
ness, the additional work becomes insignificant. These results are con
sistent with experimental observations.