The results of treatment of 1,320 patients with acute pancreatitis wer
e analysed, 460 of them had the destructive form of the disease. The h
igh significance of multicomponent etiopathogenetic treatment is demon
strated. The importance of etiotropic treatment with the application o
f endoscopic interventions, as well as treatment with cytostatics is e
mphasized. Timely combined use of these methods prevents a progressive
uncontrolled course, and reduces the volume of treatment and its dura
tion. The authors also discuss the first experience in nontraditional
management of patients with postnecrotic cavitary complications of pan
creonecrosis by the aspiration ''closed'' method with the use of ultra
sound.