M. Zeier et al., AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY-DISEASE - THE PATIENT ON RENAL REPLACEMENT THERAPY, Nephrology, dialysis, transplantation, 11, 1996, pp. 18-20
In Europe similar to 6% of all patients on chronic renal replacement t
herapy suffer from polycystic kidney disease. Survival of patients wit
h polycystic kidney disease on renal replacement therapy is better tha
n for other primary renal diseases, despite a similar cardiovascular r
isk profile. We documented a significantly higher erythropoietin level
in polycystic patients even in advanced uraemia and on dialysis. A be
tter haemoglobin level seems to improve long-term survival because of
a possible beneficial effect on cardiac function. There is no increase
d risk of renal cell carcinoma in patients with autosomal dominant pol
ycystic kidney disease. Polycystic patients on dialysis should be foll
owed for cardiac valve abnormalities and cerebral aneurysms.