PURPOSE: We herein report our experience with transanal endoscopic mic
rosurgery. The new technique combines an endoscopic view and access of
the rectum under gas insufflation via a stereoscopic telescope with a
ll conventional surgical maneuvers such as tissue preparation, coagula
tion and control of bleeding, irrigation, suction, and, finally, sutur
ing of the parietal defect. METHODS: The main indication for transanal
endoscopic microsurgery is the removal of broad-based sessile polyps
and excision of early rectal cancers. We performed local excision of p
T2, G1-2 adenocarcinomas and excision of advanced rectal cancer in hig
h-risk patients. The reported series includes 35 consecutive patients,
who have been enrolled in a prospective clinical trial. Five patients
were excluded for different reasons. The patients were submitted to 2
9 total wall excisions with or without perirectal fat and one mucosect
omy. RESULTS: Postoperative histologic examination showed 9 adenomas a
nd 21 adenocarcinomas. Morbidity included 2 (5.6 percent) perioperativ
e and 2 (5.6 percent) late complications. There was no operative morta
lity and the mean postoperative hospital course was six days. All pati
ents are in follow-up observation with a mean time of 10.3 months. In
the group of adenomas and adenocarcinomas, we did not observe local re
currence. CONCLUSIONS: Considering our experience with the overall res
ults reported by other authors, we believe that transanal endoscopic m
icrosurgery is the procedure of choice for the treatment of rectal pol
yps and early rectal cancers provided strict patient selection criteri
a are met.