A SYNTHESIS AND PROPERTIES OF 1-SUBSTITUTED 1,4,5,6-TETRAHYDROPYRIMIDINES

Authors
ALICI B CETINKAYA E CETINKAYA B
Citation
B. Alici et al., A SYNTHESIS AND PROPERTIES OF 1-SUBSTITUTED 1,4,5,6-TETRAHYDROPYRIMIDINES, Heterocycles, 45(1), 1997, pp. 29-36
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
1
Year of publication
1997
Pages
29 - 36
Database
ISI
SICI code
0385-5414(1997)45:1<29:ASAPO1>2.0.ZU;2-8
Abstract
The condensation of 1-substituted 1,3-diaminopropane with N,N-dimethyl formamide dimethylacetal gives 1-alkyl- or aryl-1,4,5,6-tetrahydropyri midines (2) and (3). Alkylation of the tetrahydropyrimidine derivative s with alkyl halides produces the 1,3-dialkyltetrahydropyrimidinium sa lts (4 and 5). The attempted dehydrogenation of 2 with sulfur leads to insertion of sulfur on the molecule.