BUDD-CHIARI SYNDROME-ASSOCIATED WITH ANTIPHOSPHOLIPID ANTIBODIES IN ACHILD - REPORT OF A CASE AND REVIEW OF THE LITERATURE

Budd-Chiari syndrome, hypertension, and thrombocytopenia developed in a 6-year-old girl as manifestations of primary antiphospholipid antibo dy syndrome (APS). She improved with systemic corticosteroid and antic oagulation therapy. Anticardiolipin antibodies were found in the patie nt, her mother and 3 siblings, suggesting the importance of genetic fa ctors. The clinical features of an APS in children is reviewed.