Consecutive electrocardiograms were recorded in 28 stroke patients wit
hout signs of primary heart disease. Individuals with subarachnoidal h
aemorrhage, or electrolyte disturbances were excluded. A computerized
tomography of the brain was performed in each case and showed a cerebr
al haemorrhage (n=4), cortical infarction (n=6), subcortical infarctio
n (n=14) and normal finding (n=4). One patient developed atrial fibril
lation but no other case of serious disturbances in rate or rhythm occ
urred. None developed AV block, bundle branch blocks or significant ch
anges in QRS complexes. The most common abnormalities in ECG were tran
sient STT changes in lateral leads, which were seen in 13 cases. The t
ypical findings were flat or slightly negative T waves, horizontal or
down-sloping ST segments and sometimes a small ST depression. In no ca
se did ECG show typical signs of acute myocardial infarction. A transi
ent prolonged QT interval was seen in three patients and transient U w
aves in four. ECG did not correlate to the location of the vascular le
sion seen on CT or the clinical outcome. It is concluded that STT chan
ges of a small magnitude are seen in about half of the cases of stroke
patients without primary heart disease and that they do not resemble
the typical pattern of acute myocardial ischaemia.