EFFECT OF CONSUMPTION OF WHOLE MILK AND SKIM MILK ON BLOOD LIPID PROFILES IN HEALTHY-MEN

A controlled crossover feeding study was conducted in eight males aged 20-36 y to compare the effects of skim milk and whole milk on blood l ipids. For 6-wk diet periods, 236 mL/4191 kJ of skim or whole milk was consumed with a background diet designed according to the American He art Association recommendations. Plasma lipids were analyzed at baseli ne and at 3 and 6 wk. After 6 wk, the mean total cholesterol concentra tion was 4.47 mmol/L with skim milk and 4.80 mmol/L with whole milk (P less than or equal to 0.001); mean low-density lipoprotein-cholestero l concentrations were 2.64 and 2.96 mmol/L, respectively (P less than or equal to 0.001). Mean apolipoprotein B decreased with skim milk and increased with whole milk (P less than or equal to 0.05). No statisti cally significant differences were observed for plasma high-density li poprotein-cholesterol, triglyceride, apolipoprotein A-I, or fatty acid s. Substitution of skim milk for whole milk may decrease the risk of c oronary heart disease.