LIGHT-MEDIATED CYCLIZATION OF )-3-(5-[6-HYDROXY-7-METHOXY]BENZOFURANYL)PROPENOIC ACID, A WATER-SOLUBLE PRECURSOR OF 8-METHOXYPSORALEN

Authors
MOHAMMAD T MORRISON H
Citation
T. Mohammad et H. Morrison, LIGHT-MEDIATED CYCLIZATION OF )-3-(5-[6-HYDROXY-7-METHOXY]BENZOFURANYL)PROPENOIC ACID, A WATER-SOLUBLE PRECURSOR OF 8-METHOXYPSORALEN, Photochemistry and photobiology, 59(2), 1994, pp. 248-251
Citations number
13
Categorie Soggetti
Biophysics,Biology
Journal title
Photochemistry and photobiology → ACNP
ISSN journal
00318655
Volume
59
Issue
2
Year of publication
1994
Pages
248 - 251
Database
ISI
SICI code
0031-8655(1994)59:2<248:LCO)>2.0.ZU;2-J
Abstract
The title compound is a stable, water-soluble ''pro-drug'' for 8-metho xypsoralen, which converts to psoralen upon photolysis with UVA light. The process involves the photolytic formation of a cis isomer that la ctonizes in a dark reaction.