ANTIMICROBIAL SUBSTANCE, 3',4'-DIHYDROXYACETOPHENONE, IN COFFEE RESIDUE

Authors
NISHINA A KAJISHIMA F MATSUNAGA M TEZUKA H INATOMI H OSAWA T
Citation
A. Nishina et al., ANTIMICROBIAL SUBSTANCE, 3',4'-DIHYDROXYACETOPHENONE, IN COFFEE RESIDUE, Bioscience, biotechnology, and biochemistry, 58(2), 1994, pp. 293-296
Citations number
15
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
58
Issue
2
Year of publication
1994
Pages
293 - 296
Database
ISI
SICI code
0916-8451(1994)58:2<293:AS3ICR>2.0.ZU;2-W
Abstract
An active antimicrobial substance contained in coffee residue was puri fied by HPLC. As result of the identification using MS, H-1-, and C-13 -NMR, etc., 3',4'-dihydroxyacetophenone was found to be the antimicrob ial substance in coffee residue. Comparison of the antimicrobial spect ra of 3',4'-dihydroxy-acetophenone isomers and catechol analogs sugges ted that the antimicrobial activity of 3',4'-dihydroxy-acetophenone is omers vary depending on the binding sites of hydroxyl groups, and the antimicrobial activity of catechol analogs was inversely proportional to the polarity of groups binding thereto.