Data from a nationally representative sample of the general population
are used to study cohort differences in the prevalence of DSM-III-R M
ajor Depressive Episode (MDE). We document increasing lifetime prevale
nce of MDE among both men and women in more recent cohorts, but no maj
or change in the sex ratio over the 40-year period retrospectively cov
ered in the survey. We find a cohort difference in 12-month MDE, with
older women much more likely than older men to have recurrent episodes
. This sex difference in recurrence plays an important part in the ele
vated 12-month prevalence of depression among women compared to men in
the 45-54 age range.