Ld. Reid et Cl. Hubbell, AN ASSESSMENT OF THE ADDICTION POTENTIAL OF THE OPIOID ASSOCIATED WITH MILK, Journal of dairy science, 77(3), 1994, pp. 672-675
Eighty-four male rats were tested to determine their preference for on
e of two distinctive places in an experimental space. After an initial
determination of place preference, rats were assigned to six groups.
They were then subjected to procedures to condition a place preference
using doses of beta-casomorphin, a standard dose of morphine, or plac
ebo. Subsequently, rats were tested for place preferences. No evidence
emerged indicating that injections of beta-casomorphin conditioned a
place preference, but evidence indicated that morphine conditioned a p
lace preference. Consequently, systemically administered beta-casomorp
hin has very limited or no reinforcing properties similar to those of
morphine. Ingestion of milk products containing beta-casomorphin is no
t likely to become the focus of an addiction.