SYNTHESIS AND CHEMISTRY OF NYL-1,2,4-TRIAZOL-3-YL)-3-PHENYL-4(3H)-QUINAZOLONE

Several yl-1-(3-phenyl-4(3H)-oxo-2-quinazolinylthioacetyl) thiosemicar bazide (4) and nyl-1,2,4-triazol-3-yl)-3-phenyl-4(3H)-quinazolone (5) have been synthesised by condensation of 3-Phenyl-4(3H)-oxo-2-quinazol inyl-thioacetyl hydrazine (3) with phenyl isothiocyanate. Subsequent r ing closure of the substituted thiosemicarbazide yielded the triazole thiol (5). The reactions of triazole thiol (5) towards alkylation, 4-c hlorbenzene sulphonyl chloride, activated olefinic compounds and antbr anilic acid have been reported.